Mus musculus Protein: Thbs3
Summary
InnateDB Protein IDBP-163289.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Thbs3
Protein Name thrombospondin 3
Synonyms Thbs-3; TSP3;
Species Mus musculus
Ensembl Protein ENSMUSP00000029682
InnateDB Gene IDBG-163287 (Thbs3)
Protein Structure
UniProt Annotation
Function Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
Subcellular Localization
Disease Associations
Tissue Specificity Brain, lung and cartilage.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008201 heparin binding
Biological Process
GO:0003417 growth plate cartilage development
GO:0007155 cell adhesion
GO:0043931 ossification involved in bone maturation
GO:0060346 bone trabecula formation
Cellular Component
GO:0005576 extracellular region
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:98739
InterPro IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR003367 Thrombospondin, type 3-like repeat
IPR008859 Thrombospondin, C-terminal
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR024665 Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain
IPR028974 TSP type-3 repeat
PFAM PF00008
PF00054
PF02210
PF07645
PF02412
PF05735
PF11598
PRINTS
PIRSF
SMART SM00181
SM00210
SM00282
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q05895
PhosphoSite PhosphoSite-Q05895
TrEMBL Q8K3G4
UniProt Splice Variant
Entrez Gene 21827
UniGene Mm.2114
RefSeq NP_038719
MGI ID
MGI Symbol Thbs3
OMIM
CCDS CCDS17495
HPRD
IMGT
EMBL AY115108 BC053023 CH466547 L04302 L24434 M86611 M86612 M86613 M86614 M86615 M86616 M86617 M86618 M86619 M86620 U16175 U66257
GenPept AAA40430 AAA40433 AAA40497 AAA98537 AAC52819 AAH53023 AAM66759 EDL15225