InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Umodl1

Summary

InnateDB Protein

IDBP-163365.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Umodl1

Protein Name

uromodulin-like 1

Synonyms

D17Ertd488e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000067443

InnateDB Gene

IDBG-163363 (Umodl1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cell membrane {ECO:0000269PubMed:16026467}; Single-pass type I membrane protein {ECO:0000269PubMed:16026467}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0030414	peptidase inhibitor activity

Biological Process

GO:0007338	single fertilization
GO:0010466	negative regulation of peptidase activity
GO:0010468	regulation of gene expression
GO:0042981	regulation of apoptotic process
GO:0048609	multicellular organismal reproductive process
GO:0060612	adipose tissue development
GO:0097211	cellular response to gonadotropin-releasing hormone
GO:2000354	regulation of ovarian follicle development

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0009897	external side of plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1929785

InterPro

IPR000082 SEA domain
IPR000742 Epidermal growth factor-like domain
IPR001507 Zona pellucida domain
IPR001881 EGF-like calcium-binding domain
IPR003961 Fibronectin, type III
IPR008197 Whey acidic protein-type 4-disulphide core
IPR011489 EMI domain

PFAM