InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LAMA3

Summary

InnateDB Protein

IDBP-1635.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LAMA3

Protein Name

laminin, alpha 3

Synonyms

BM600; E170; lama3a; LAMNA; LOCS;

Species

Homo sapiens

Ensembl Protein

ENSP00000269217

InnateDB Gene

IDBG-1631 (LAMA3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0004871	signal transducer activity
GO:0005102	receptor binding
GO:0005198	structural molecule activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007155	cell adhesion
GO:0007165	signal transduction
GO:0008544	epidermis development
GO:0022617	extracellular matrix disassembly
GO:0030155	regulation of cell adhesion
GO:0030198	extracellular matrix organization
GO:0030334	regulation of cell migration
GO:0031581	hemidesmosome assembly
GO:0034329	cell junction assembly
GO:0045995	regulation of embryonic development

Cellular Component

GO:0005576	extracellular region
GO:0005604	basement membrane
GO:0005606	laminin-1 complex

Protein Structure and Domains

PDB ID

InterPro

IPR001791 Laminin G domain
IPR002049 EGF-like, laminin
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR009254 Laminin I
IPR010307 Laminin domain II
IPR015988 STAT transcription factor, coiled coil

PFAM

PF00054
PF02210
PF00053
PF06008
PF06009

PRINTS

PIRSF

SMART

SM00210
SM00282
SM00180

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q16787