Version 5.4
Mus musculus Protein: Rps19bp1
Summary
InnateDB Protein IDBP-163631.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rps19bp1
Protein Name ribosomal protein S19 binding protein 1
Synonyms 2510038A11Rik; AI604923; S19BP;
Species Mus musculus
Ensembl Protein ENSMUSP00000061167
InnateDB Gene IDBG-163629 (Rps19bp1)
Protein Structure
UniProt Annotation
Function Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:16289379}.
Disease Associations
Tissue Specificity Widely expressed with higher levels in submaxillary gland and epididymis. {ECO:0000269PubMed:16289379}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1913788
InterPro IPR023262 Active regulator of SIRT1
PFAM
PRINTS PR02029
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C6B9
PhosphoSite PhosphoSite-Q8C6B9
TrEMBL
UniProt Splice Variant
Entrez Gene 66538
UniGene
RefSeq NP_780318
MGI ID
MGI Symbol Rps19bp1
OMIM
CCDS CCDS27662
HPRD
IMGT
EMBL AB233218 AB233219 AK075974 BC038691 BC050115
GenPept AAH38691 AAH50115 BAC36088 BAE53365 BAE53366

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca