Version 5.4
Mus musculus Protein: Pgpep1
Summary
InnateDB Protein IDBP-163765.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pgpep1
Protein Name pyroglutamyl-peptidase I
Synonyms 2810003H13Rik; Gm19458; PAP-I; Pcp; PGP; PGP-I; PGPI;
Species Mus musculus
Ensembl Protein ENSMUSP00000070778
InnateDB Gene IDBG-163763 (Pgpep1)
Protein Structure
UniProt Annotation
Function Removes 5-oxoproline from various penultimate amino acid residues except L-proline. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1913772
InterPro IPR000816 Peptidase C15, pyroglutamyl peptidase I
IPR016125 Peptidase C15, pyroglutamyl peptidase I-like
PFAM PF01470
PRINTS PR00706
PIRSF PIRSF015592
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ESW8
PhosphoSite PhosphoSite-Q9ESW8
TrEMBL
UniProt Splice Variant
Entrez Gene 66522
UniGene Mm.490914
RefSeq NP_075706
MGI ID
MGI Symbol Pgpep1
OMIM
CCDS CCDS22377
HPRD
IMGT
EMBL AJ278829 AK003373 AK012658 AK047835 AK049632 BC051938
GenPept AAH51938 BAB22746 BAB28388 BAC33170 BAC33848 CAC03615

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca