Version 5.4
Mus musculus Protein: Cd96
Summary
InnateDB Protein IDBP-163877.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd96
Protein Name CD96 antigen
Synonyms 1700109I12Rik; Tactile;
Species Mus musculus
Ensembl Protein ENSMUSP00000023336
InnateDB Gene IDBG-163875 (Cd96)
Protein Structure
UniProt Annotation
Function May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1934368
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF08205
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U0X8
PhosphoSite PhosphoSite-Q3U0X8
TrEMBL
UniProt Splice Variant
Entrez Gene 84544
UniGene
RefSeq NP_115854
MGI ID
MGI Symbol Cd96
OMIM
CCDS CCDS37348
HPRD
IMGT
EMBL AK040539 AK156470 AY029156 BC052865
GenPept AAH52865 AAK31788 BAC30620 BAE33723

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca