Mus musculus Protein: Fbxo17
Summary
InnateDB Protein IDBP-164037.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo17
Protein Name F-box protein 17
Synonyms Fbg4; Fbx17; Fbxo26;
Species Mus musculus
Ensembl Protein ENSMUSP00000032818
InnateDB Gene IDBG-164035 (Fbxo17)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed primarily in the brain. {ECO:0000269PubMed:18203720}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0019005 SCF ubiquitin ligase complex
Protein Structure and Domains
PDB ID MGI:1354707
InterPro IPR001810 F-box domain
IPR007397 F-box associated (FBA) domain
IPR008979 Galactose-binding domain-like
PFAM PF00646
PF12937
PF13013
PF04300
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZM8
PhosphoSite PhosphoSite-
TrEMBL Q3V064
UniProt Splice Variant
Entrez Gene 50760
UniGene Mm.358659
RefSeq NP_056611
MGI ID
MGI Symbol Fbxo17
OMIM
CCDS CCDS39863
HPRD
IMGT
EMBL AF176532 AK133408 BC026470 CH466593
GenPept AAF09141 AAH26470 BAE21641 EDL24123