Mus musculus Protein: Cyp2c54
Summary
InnateDB Protein IDBP-164285.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cyp2c54
Protein Name cytochrome P450, family 2, subfamily c, polypeptide 54
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000048284
InnateDB Gene IDBG-164283 (Cyp2c54)
Protein Structure
UniProt Annotation
Function Metabolizes arachidonic acid mainly to 12- hydroxyeicosatetraenoic acid (HETE). {ECO:0000269PubMed:15102943}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:15102943}; Peripheral membrane protein {ECO:0000269PubMed:15102943}. Microsome membrane {ECO:0000269PubMed:15102943}; Peripheral membrane protein {ECO:0000269PubMed:15102943}.
Disease Associations
Tissue Specificity Expressed in liver. {ECO:0000269PubMed:15102943}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0070330 aromatase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID MGI:3642960
InterPro IPR001128 Cytochrome P450
IPR002397 Cytochrome P450, B-class
IPR002401 Cytochrome P450, E-class, group I
IPR002403 Cytochrome P450, E-class, group IV
PFAM PF00067
PRINTS PR00385
PR00359
PR00463
PR00465
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6XVG2
PhosphoSite PhosphoSite-Q6XVG2
TrEMBL
UniProt Splice Variant
Entrez Gene 404195
UniGene Mm.379575
RefSeq NP_996260
MGI ID
MGI Symbol Cyp2c54
OMIM
CCDS CCDS29800
HPRD
IMGT
EMBL AY206874
GenPept AAO52737