Version 5.4
Homo sapiens Protein: FOPNL
Summary
InnateDB Protein IDBP-16435.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOPNL
Protein Name FGFR1OP N-terminal like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000255759
InnateDB Gene IDBG-16433 (FOPNL)
Protein Structure
UniProt Annotation
Function Involved in the biogenesis of cilia. {ECO:0000269PubMed:20551181}.
Subcellular Localization Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:20551181}. Cytoplasmic granule {ECO:0000269PubMed:20551181}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269PubMed:20551181}.
Disease Associations
Tissue Specificity Widely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine. {ECO:0000269PubMed:20551181}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0034453 microtubule anchoring
GO:0042384 cilium assembly
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0031514 motile cilium
GO:0034451 centriolar satellite
GO:0036064 ciliary basal body
Protein Structure and Domains
PDB ID
InterPro IPR006594 LisH dimerisation motif
IPR018993 FGFR1 oncogene partner (FOP), N-terminal dimerisation domain
PFAM PF09398
PRINTS
PIRSF
SMART SM00667
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96NB1
PhosphoSite PhosphoSite-Q96NB1
TrEMBL I3L2N4
UniProt Splice Variant
Entrez Gene 123811
UniGene Hs.602416
RefSeq NP_653201
HUGO HGNC:26435
OMIM
CCDS CCDS10567
HPRD 08096
IMGT
EMBL AC130651 AK055715 AY507846 BC022321
GenPept AAH22321 AAR98812 BAB70994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca