Version 5.4
| Mus musculus Protein: Rinl | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-164448.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Rinl | ||||||||
| Protein Name | Ras and Rab interactor-like | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000058447 | ||||||||
| InnateDB Gene | IDBG-164446 (Rinl) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Guanine nucleotide exchange factor (GEF) for RAB5A and RAB22A that activates RAB5A and RAB22A by exchanging bound GDP for free GTP. Plays a role in endocytosis via its role in activating Rab family members. {ECO:0000269PubMed:21419809}. | ||||||||
| Subcellular Localization | Cell projection, ruffle {ECO:0000269PubMed:21419809}. Cytoplasmic vesicle {ECO:0000269PubMed:21419809}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Detected in thymus and spleen (at protein level). Detected in lung, liver, kidney, spleen, thymus and skeletal muscle. {ECO:0000269PubMed:21419809}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2444024 | ||||||||
| InterPro |
IPR000980
SH2 domain IPR003123 Vacuolar sorting protein 9 IPR013995 Vacuolar sorting protein 9, subgroup |
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| PFAM |
PF00017
PF14633 PF02204 |
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| PRINTS |
PR00401
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| PIRSF | |||||||||
| SMART |
SM00252
SM00167 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q80UW3 | ||||||||
| PhosphoSite | PhosphoSite-Q80UW3 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 320435 | ||||||||
| UniGene | Mm.74632 | ||||||||
| RefSeq | NP_796132 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Rinl | ||||||||
| OMIM | |||||||||
| CCDS | CCDS21056 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK030993 AK082828 AK162469 AK168472 BC044878 BC046530 | ||||||||
| GenPept | AAH44878 AAH46530 BAC27206 BAC38641 BAE36936 BAE40363 | ||||||||