Mus musculus Protein: Abca12
Summary
InnateDB Protein IDBP-164511.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Abca12
Protein Name ATP-binding cassette, sub-family A (ABC1), member 12
Synonyms 4832428G11Rik; 4833417A11Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000084523
InnateDB Gene IDBG-164509 (Abca12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005102 receptor binding
GO:0005319 lipid transporter activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0034191 apolipoprotein A-I receptor binding
Biological Process
GO:0006200 ATP catabolic process
GO:0010875 positive regulation of cholesterol efflux
GO:0030216 keratinocyte differentiation
GO:0031424 keratinization
GO:0032940 secretion by cell
GO:0033700 phospholipid efflux
GO:0035627 ceramide transport
GO:0043129 surfactant homeostasis
GO:0045055 regulated secretory pathway
GO:0048286 lung alveolus development
GO:0055088 lipid homeostasis
GO:0061436 establishment of skin barrier
GO:0072659 protein localization to plasma membrane
GO:2000010 positive regulation of protein localization to cell surface
Cellular Component
GO:0005737 cytoplasm
GO:0005743 mitochondrial inner membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0097209 epidermal lamellar body
Protein Structure and Domains
PDB ID MGI:2676312
InterPro IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00005
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-NP_780419
TrEMBL E9Q876
UniProt Splice Variant
Entrez Gene 74591
UniGene Mm.159251
RefSeq NP_780419
MGI ID
MGI Symbol Abca12
OMIM
CCDS CCDS48286
HPRD
IMGT
EMBL AC107789 AC138589
GenPept