InnateDB Protein
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IDBP-164575.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Slc25a17
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Protein Name
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solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
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Synonyms
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34kDa; 47kDa; PMP34; Pmp47;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000023040
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InnateDB Gene
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IDBG-164573 (Slc25a17)
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Protein Structure
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Function |
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5'-phosphate and bathophenanthroline in vitro (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Peroxisome membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Expressed in liver.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1342248
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InterPro |
IPR002067
Mitochondrial carrier protein
IPR018108
Mitochondrial substrate/solute carrier
IPR023395
Mitochondrial carrier domain
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PFAM |
PF00153
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PRINTS |
PR00926
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O70579
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
20524
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UniGene |
Mm.465499
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RefSeq |
NP_035529
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MGI ID |
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MGI Symbol |
Slc25a17
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OMIM |
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CCDS |
CCDS27666
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HPRD |
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IMGT |
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EMBL |
AJ006341
AK002388
BC008571
BC011292
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GenPept |
AAH08571
AAH11292
BAB22062
CAA06984
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