Version 5.4
Mus musculus Protein: Lgals4
Summary
InnateDB Protein IDBP-164734.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lgals4
Protein Name lectin, galactose binding, soluble 4
Synonyms gal-4;
Species Mus musculus
Ensembl Protein ENSMUSP00000066461
InnateDB Gene IDBG-164732 (Lgals4)
Protein Structure
UniProt Annotation
Function Galectin that binds lactose and a related range of sugars. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Epithelial cells of the embryonic and adult gastrointestinal tract. Expressed at about equal levels in colon and small intestine but much less in stomach. {ECO:0000269PubMed:9446608}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID MGI:107536
InterPro IPR001079 Galectin, carbohydrate recognition domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00337
PRINTS
PIRSF
SMART SM00276
SM00908
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K419
PhosphoSite PhosphoSite-Q8K419
TrEMBL Q3UL35
UniProt Splice Variant
Entrez Gene 16855
UniGene Mm.210336
RefSeq NP_034836
MGI ID 3I8T
MGI Symbol Lgals4
OMIM
CCDS CCDS21058
HPRD
IMGT
EMBL AF026795 AF510729 AK145734 AY044870 BC011236 BC021632 BC030297 BC141106 BC145387 CH466593 EF494107
GenPept AAC27245 AAH11236 AAH21632 AAH30297 AAI41107 AAI45388 AAK97790 AAM44060 ABU55923 BAE26616 EDL24106

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca