InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cyp2j5

Summary

InnateDB Protein

IDBP-164798.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cyp2j5

Protein Name

cytochrome P450, family 2, subfamily j, polypeptide 5

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030299

InnateDB Gene

IDBG-164796 (Cyp2j5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0070330	aromatase activity

Biological Process

GO:0001990	regulation of systemic arterial blood pressure by hormone
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0055114	oxidation-reduction process
GO:0097254	renal tubular secretion
GO:2000863	positive regulation of estrogen secretion

Cellular Component

GO:0005789

endoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

MGI:1270149

InterPro

IPR001128 Cytochrome P450
IPR002397 Cytochrome P450, B-class
IPR002401 Cytochrome P450, E-class, group I
IPR002403 Cytochrome P450, E-class, group IV
IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
IPR008071 Cytochrome P450, E-class, group I, CYP2J-like

PFAM

PF00067

PRINTS

PR00385
PR00359
PR00463
PR00465
PR01686
PR01688

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O54749