Version 5.4
Mus musculus Protein: Pcbp1
Summary
InnateDB Protein IDBP-164863.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcbp1
Protein Name poly(rC) binding protein 1
Synonyms [a]CP-1; alphaCP-1; WBP17;
Species Mus musculus
Ensembl Protein ENSMUSP00000054863
InnateDB Gene IDBG-164861 (Pcbp1)
Protein Structure
UniProt Annotation
Function Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 84 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 84 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008494 translation activator activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0045087 innate immune response (InnateDB)
GO:0045727 positive regulation of translation
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1345635
InterPro IPR004044 K Homology domain, type 2
IPR004087 K Homology domain
IPR004088 K Homology domain, type 1
PFAM PF07650
PF00013
PF13014
PRINTS
PIRSF
SMART SM00322
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P60335
PhosphoSite PhosphoSite-P60335
TrEMBL
UniProt Splice Variant
Entrez Gene 23983
UniGene Mm.382665
RefSeq NP_035995
MGI ID
MGI Symbol Pcbp1
OMIM
CCDS CCDS20314
HPRD
IMGT
EMBL AF139894 AF139895 BC004793 BC069915
GenPept AAD51920 AAD51921 AAH04793 AAH69915

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca