Version 5.4
Homo sapiens Protein: CATSPERB
Summary
InnateDB Protein IDBP-16493.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CATSPERB
Protein Name cation channel, sperm-associated, beta
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000256343
InnateDB Gene IDBG-16491 (CATSPERB)
Protein Structure
UniProt Annotation
Function Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007338 single fertilization
GO:0030154 cell differentiation
GO:0032504 multicellular organism reproduction
GO:0035036 sperm-egg recognition
Cellular Component
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0036128 CatSper complex
Protein Structure and Domains
PDB ID
InterPro IPR011040 Sialidases
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H7T0
PhosphoSite PhosphoSite-Q9H7T0
TrEMBL G3V584
UniProt Splice Variant
Entrez Gene 79820
UniGene Hs.131755
RefSeq NP_079040
HUGO HGNC:20500
OMIM 611169
CCDS CCDS32142
HPRD 16613
IMGT
EMBL AK024360 AL121839 AL133373 BC126214 BC126216
GenPept AAI26215 AAI26217 BAB14896

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca