Version 5.4
Mus musculus Protein: Sox30
Summary
InnateDB Protein IDBP-164970.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sox30
Protein Name SRY-box containing gene 30
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000037519
InnateDB Gene IDBG-164968 (Sox30)
Protein Structure
UniProt Annotation
Function Transcriptional activator. Binds to the DNA sequence 5'- ACAAT-3' and shows a preference for guanine residues surrounding this core motif (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00267}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007283 spermatogenesis
GO:0031960 response to corticosteroid
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1341157
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CGW4
PhosphoSite PhosphoSite-Q8CGW4
TrEMBL
UniProt Splice Variant
Entrez Gene 214105
UniGene Mm.66708
RefSeq NP_775560
MGI ID
MGI Symbol Sox30
OMIM
CCDS CCDS24570
HPRD
IMGT
EMBL AY005801
GenPept AAF99391

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca