InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gmcl1

Summary

InnateDB Protein

IDBP-165012.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gmcl1

Protein Name

germ cell-less homolog 1 (Drosophila)

Synonyms

2810049L19Rik; Gcl; mglc-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000001185

InnateDB Gene

IDBG-165010 (Gmcl1)

Protein Structure

UniProt Annotation

Function

Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport.

Subcellular Localization

Nucleus matrix.

Disease Associations

Tissue Specificity

Ubiquitously expressed at low levels throughout development and in adult tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0030154	cell differentiation