InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nipal4

Summary

InnateDB Protein

IDBP-165253.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nipal4

Protein Name

NIPA-like domain containing 4

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020679

InnateDB Gene

IDBG-165251 (Nipal4)

Protein Structure

UniProt Annotation

Function

Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0015095	magnesium ion transmembrane transporter activity

Biological Process

GO:0015693

magnesium ion transport

Cellular Component

GO:0005575	cellular_component
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2444671

InterPro

IPR000620 Drug/metabolite transporter
IPR008521 Magnesium transporter NIPA

PFAM

PF00892
PF05653

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BZF2

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

214112

UniGene

Mm.225253

RefSeq

NP_766112

MGI ID

MGI Symbol

Nipal4

OMIM

CCDS

CCDS24572

HPRD

IMGT

EMBL

AK035561 AL663031 AL713958 BC139819 CH466575

GenPept

AAI39820 BAC29107 CAI25033 CAI25369 EDL33826