Version 5.4
Mus musculus Protein: Opalin
Summary
InnateDB Protein IDBP-165438.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Opalin
Protein Name oligodendrocytic myelin paranodal and inner loop protein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000084422
InnateDB Gene IDBG-165436 (Opalin)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000269PubMed:18439243, ECO:0000269PubMed:18490449}; Single-pass type I membrane protein {ECO:0000269PubMed:18439243, ECO:0000269PubMed:18490449}. Note=In the CNS, enriched in the myelin paranodal and inner loop membranes, but not that of the PNS.
Disease Associations
Tissue Specificity Expressed specifically in oligodendrocytes of the brain. {ECO:0000269PubMed:17442045, ECO:0000269PubMed:18439243, ECO:0000269PubMed:18490449}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2657025
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7M750
PhosphoSite PhosphoSite-Q7M750
TrEMBL Q3USW3
UniProt Splice Variant
Entrez Gene 226115
UniGene Mm.54119
RefSeq NP_705740
MGI ID
MGI Symbol Opalin
OMIM
CCDS CCDS37985
HPRD
IMGT
EMBL AK140031 BC060980 BK000002 CH466534
GenPept AAH60980 BAE24217 DAA00020 EDL41851

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca