Version 5.4
Mus musculus Protein: Gkn3
Summary
InnateDB Protein IDBP-165737.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gkn3
Protein Name gastrokine 3
Synonyms 1190003M12Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000032127
InnateDB Gene IDBG-165735 (Gkn3)
Protein Structure
UniProt Annotation
Function Inhibits gastric epithelial cell proliferation. {ECO:0000269PubMed:20138039}.
Subcellular Localization Secreted {ECO:0000269PubMed:20138039}.
Disease Associations
Tissue Specificity Expressed in stomach. Present in mucus cells at the base of antral glands, and Brunner glands of the duodenum. Present at lower levels in the mucus neck cell region of the fundus (at protein level). {ECO:0000269PubMed:20138039}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0050680 negative regulation of epithelial cell proliferation
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:1916138
InterPro IPR007084 BRICHOS domain
PFAM PF04089
PRINTS
PIRSF
SMART SM01039
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D0T7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 68888
UniGene
RefSeq NP_081136
MGI ID
MGI Symbol Gkn3
OMIM
CCDS CCDS20320
HPRD
IMGT
EMBL AK004474 BC116955 CH466523 FN600638 GU220566
GenPept AAI16956 ADB22387 BAB23320 CBI70313 EDK99205

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca