Version 5.4
Mus musculus Protein: Arhgap25
Summary
InnateDB Protein IDBP-165787.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap25
Protein Name Rho GTPase activating protein 25
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000098758
InnateDB Gene IDBG-165785 (Arhgap25)
Protein Structure
UniProt Annotation
Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:2443687
InterPro IPR000198 Rho GTPase-activating protein domain
IPR001849 Pleckstrin homology domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PF00169
PRINTS
PIRSF
SMART SM00324
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BYW1
PhosphoSite PhosphoSite-Q8BYW1
TrEMBL
UniProt Splice Variant
Entrez Gene 232201
UniGene Mm.403320
RefSeq NP_780685
MGI ID
MGI Symbol Arhgap25
OMIM
CCDS CCDS20322
HPRD
IMGT
EMBL AK037710 AK137444 AK159598 AK159941 AK169897 AK172878 BC108400 BC138751
GenPept AAI08401 AAI38752 BAC29857 BAD32156 BAE23353 BAE35218 BAE35498 BAE41444

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca