InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adcy4

Summary

InnateDB Protein

IDBP-165828.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adcy4

Protein Name

adenylate cyclase 4

Synonyms

mKIAA4004;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000002398

InnateDB Gene

IDBG-165826 (Adcy4)

Protein Structure

UniProt Annotation

Function

This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. {ECO:0000250}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004016	adenylate cyclase activity
GO:0005524	ATP binding
GO:0016849	phosphorus-oxygen lyase activity
GO:0046872	metal ion binding

Biological Process

GO:0006171	cAMP biosynthetic process
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007190	activation of adenylate cyclase activity
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0030425	dendrite

Protein Structure and Domains

PDB ID

MGI:99674

InterPro

IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
IPR009398 Adenylate cyclase-like

PFAM

PF00211
PF06327

PRINTS

PIRSF

SMART

SM00044

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91WF3

PhosphoSite

PhosphoSite-Q91WF3

TrEMBL

UniProt Splice Variant

Entrez Gene

104110

UniGene

RefSeq

NP_536683

MGI ID

MGI Symbol

Adcy4

OMIM

CCDS

CCDS27130

HPRD

IMGT

EMBL

AF442771 BC015299

GenPept

AAH15299 AAL38004