InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acat1

Summary

InnateDB Protein

IDBP-165953.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acat1

Protein Name

acetyl-Coenzyme A acetyltransferase 1

Synonyms

6330585C21Rik; Acat;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034547

InnateDB Gene

IDBG-165951 (Acat1)

Protein Structure

UniProt Annotation

Function

Plays a major role in ketone body metabolism. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003985	acetyl-CoA C-acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
GO:0019899	enzyme binding
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0050662	coenzyme binding

Biological Process

GO:0001889	liver development
GO:0007420	brain development
GO:0008152	metabolic process
GO:0009725	response to hormone
GO:0014070	response to organic cyclic compound
GO:0042594	response to starvation
GO:0051260	protein homooligomerization
GO:0060612	adipose tissue development
GO:0072229	metanephric proximal convoluted tubule development