Version 5.4
Mus musculus Protein: Havcr1
Summary
InnateDB Protein IDBP-165961.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Havcr1
Protein Name hepatitis A virus cellular receptor 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000043827
InnateDB Gene IDBG-165957 (Havcr1)
Protein Structure
UniProt Annotation
Function May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed by stimulated T-cells. Expressed during primary antigen stimulation. {ECO:0000269PubMed:11725301}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0033005 positive regulation of mast cell activation
Cellular Component
Protein Structure and Domains
PDB ID MGI:2159680
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q5QNS5
TrEMBL E9QPA7
UniProt Splice Variant
Entrez Gene 171283
UniGene Mm.413433
RefSeq NP_599009
MGI ID
MGI Symbol Havcr1
OMIM
CCDS CCDS24583
HPRD
IMGT
EMBL AL669892
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca