Mus musculus Protein: Nhp2l1
Summary
InnateDB Protein IDBP-165984.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nhp2l1
Protein Name NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000091840
InnateDB Gene IDBG-165982 (Nhp2l1)
Protein Structure
UniProt Annotation
Function Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
Experimentally validated
Total 47 [view]
Protein-Protein 47 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005681 spliceosomal complex
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID MGI:893586
InterPro IPR000948 Ribosomal protein L7Ae, prokaryotes
IPR002415 H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote
IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45
IPR013241 RNase P, subunit Pop3
IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family
IPR029064 50S ribosomal protein L30e-like
PFAM PF01248
PF08228
PRINTS PR00884
PR00883
PR00881
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D0T1
PhosphoSite PhosphoSite-Q9D0T1
TrEMBL
UniProt Splice Variant
Entrez Gene 20826
UniGene Mm.464206
RefSeq NP_035612
MGI ID
MGI Symbol Nhp2l1
OMIM
CCDS CCDS37154
HPRD
IMGT
EMBL AK004489 AK134943 AK145608 AK168930 AK169103 BC026755 BC054450 BC083315 U95114
GenPept AAC53177 AAH26755 AAH54450 AAH83315 BAB23329 BAE22349 BAE26537 BAE40743 BAE40885