Version 5.4
Mus musculus Protein: Nxnl1
Summary
InnateDB Protein IDBP-166042.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nxnl1
Protein Name nucleoredoxin-like 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000039294
InnateDB Gene IDBG-166040 (Nxnl1)
Protein Structure
UniProt Annotation
Function May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods. {ECO:0000269PubMed:15220920}.
Subcellular Localization Nucleus outer membrane {ECO:0000269PubMed:15220920}.
Disease Associations
Tissue Specificity Retina-specific. Expressed predominantly by photoreceptors, expression mainly restricted to the outer nuclear layer containing the rods and cones.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005640 nuclear outer membrane
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1924446
InterPro IPR012336 Thioredoxin-like fold
PFAM PF13098
PF13192
PF13462
PF13905
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VC33
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 234404
UniGene Mm.213208
RefSeq XP_006544407
MGI ID
MGI Symbol Nxnl1
OMIM
CCDS CCDS40385
HPRD
IMGT
EMBL BC021911
GenPept AAH21911

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca