InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gp9

Summary

InnateDB Protein

IDBP-166096.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gp9

Protein Name

glycoprotein 9 (platelet)

Synonyms

Cd42; GPIX;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032133

InnateDB Gene

IDBG-166094 (Gp9)

Protein Structure

UniProt Annotation

Function

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0007155	cell adhesion
GO:0007596	blood coagulation
GO:0008150	biological_process

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1860137

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal

PFAM

PF01462
PF01463

PRINTS

PIRSF

SMART

SM00013
SM00082

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O88186

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

54368

UniGene

RefSeq

NP_061232

MGI ID

MGI Symbol

Gp9

OMIM

CCDS

CCDS20328

HPRD

IMGT

EMBL

AB007464 BC111106 CH466523

GenPept

AAI11107 BAA31694 EDK99218