Version 5.4
Mus musculus Protein: Trmt10c
Summary
InnateDB Protein IDBP-166373.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trmt10c
Protein Name RNA (guanine-9-) methyltransferase domain containing 1
Synonyms 1300018J16Rik; D16Ertd454e; Rg9mtd1; Rnmtd1;
Species Mus musculus
Ensembl Protein ENSMUSP00000058954
InnateDB Gene IDBG-166371 (Trmt10c)
Protein Structure
UniProt Annotation
Function Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000964 mitochondrial RNA 5'-end processing
GO:0008033 tRNA processing
GO:0032259 methylation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
Protein Structure and Domains
PDB ID MGI:1196261
InterPro IPR016009 tRNA methyltransferase TRMD/TRM10-type domain
PFAM PF01746
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UFY8
PhosphoSite PhosphoSite-Q3UFY8
TrEMBL
UniProt Splice Variant
Entrez Gene 52575
UniGene Mm.417313
RefSeq NP_083368
MGI ID
MGI Symbol Trmt10c
OMIM
CCDS CCDS28220
HPRD
IMGT
EMBL AK005047 AK087991 AK135426 AK148219 AK166781 BC023147 BC106131
GenPept AAH23147 AAI06132 BAB23773 BAC40080 BAE22529 BAE28421 BAE39015

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca