InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Alg6

Summary

InnateDB Protein

IDBP-166491.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Alg6

Protein Name

asparagine-linked glycosylation 6 homolog (yeast, alpha-1,3,-glucosyltransferase)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095574

InnateDB Gene

IDBG-166489 (Alg6)

Protein Structure

UniProt Annotation

Function

Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016758	transferase activity, transferring hexosyl groups
GO:0046527	glucosyltransferase activity

Biological Process

GO:0006487

protein N-linked glycosylation

Cellular Component

GO:0005575	cellular_component
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2444031

InterPro

IPR004856 Glycosyl transferase, ALG6/ALG8

PFAM

PF03155

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3TAE8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

320438

UniGene

Mm.472131

RefSeq

NP_001074733

MGI ID

MGI Symbol

Alg6

OMIM

CCDS

CCDS38818

HPRD

IMGT

EMBL

AK157903 AK171887 BC050854 BX005053

GenPept

AAH50854 BAE34254 BAE42720 CAM22176