InnateDB Protein
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IDBP-166616.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pnkd
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Protein Name
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paroxysmal nonkinesiogenic dyskinesia
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Synonyms
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2210013N15Rik; 2810403H05Rik; AI854243; Brp17; MNCb-5687; MR-1; Tahccp2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000084477
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InnateDB Gene
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IDBG-166610 (Pnkd)
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Protein Structure
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Function |
Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa- B signaling pathway. {ECO:0000269PubMed:17420335}.
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Subcellular Localization |
Isoform 1: Membrane; Peripheral membrane protein.Isoform 2: Cytoplasm. Nucleus.Isoform 4: Mitochondrion {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in many discrete areas of the brain. {ECO:0000269PubMed:15496428}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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|
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Molecular Function |
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Biological Process |
GO:0006750
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glutathione biosynthetic process
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GO:0032225
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regulation of synaptic transmission, dopaminergic
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GO:0042053
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regulation of dopamine metabolic process
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GO:0050884
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neuromuscular process controlling posture
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Cellular Component |
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PDB ID |
MGI:1930773
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InterPro |
IPR001279
Beta-lactamase-like
IPR017782
Hydroxyacylglutathione hydrolase
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PFAM |
PF00753
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PRINTS |
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PIRSF |
PIRSF005457
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SMART |
SM00849
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TIGRFAMs |
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Modification |
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SwissProt |
Q69ZP3
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PhosphoSite |
PhosphoSite-Q69ZP3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
56695
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UniGene |
Mm.415421
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RefSeq |
NP_064383
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MGI ID |
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MGI Symbol |
Pnkd
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OMIM |
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CCDS |
CCDS15045
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HPRD |
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IMGT |
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EMBL |
AB041609
AF318058
AK009545
AK012976
AK041238
AK166548
AK173125
AY039041
AY039042
AY299972
BC008274
BC058945
BC116236
BC116237
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GenPept |
AAH08274
AAH58945
AAI16237
AAI16238
AAK83447
AAK83448
AAL25717
AAP58373
BAA95092
BAB26351
BAB28577
BAC30873
BAD32403
BAE38846
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