InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ugdh

Summary

InnateDB Protein

IDBP-166622.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ugdh

Protein Name

UDP-glucose dehydrogenase

Synonyms

Udpgdh;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031103

InnateDB Gene

IDBG-166620 (Ugdh)

Protein Structure

UniProt Annotation

Function

Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. {ECO:0000269PubMed:9737970}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003979	UDP-glucose 6-dehydrogenase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287	NAD binding

Biological Process

GO:0001702	gastrulation with mouth forming second
GO:0006065	UDP-glucuronate biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1306785

InterPro

IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation
IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal
IPR017476 UDP-glucose/GDP-mannose dehydrogenase

PFAM

PF03721
PF00984
PF03720

PRINTS

PIRSF

PIRSF000124

SMART

SM00984

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt