Version 5.4
Mus musculus Protein: Mcpt8
Summary
InnateDB Protein IDBP-166672.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mcpt8
Protein Name mast cell protease 8
Synonyms BB139338; MMCP-8;
Species Mus musculus
Ensembl Protein ENSMUSP00000015594
InnateDB Gene IDBG-166670 (Mcpt8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000250}. Cytoplasmic granule {ECO:0000250}. Note=Secretory granules. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008626 granzyme-mediated apoptotic signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID MGI:1261780
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P43430
PhosphoSite PhosphoSite-
TrEMBL Q3UWB6
UniProt Splice Variant
Entrez Gene 17231
UniGene
RefSeq NP_032598
MGI ID
MGI Symbol Mcpt8
OMIM
CCDS CCDS27141
HPRD
IMGT
EMBL AF119362 AF119363 AK136485 BC119342 BC120607 CH466535 X78545
GenPept AAD43899 AAD43900 AAI19343 AAI20608 BAE23000 CAA55291 EDL36216

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca