InnateDB Protein
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IDBP-166745.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cib2
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Protein Name
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calcium and integrin binding family member 2
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Synonyms
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2810434I23Rik; AI449053;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000038527
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InnateDB Gene
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IDBG-166743 (Cib2)
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Protein Structure
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Function |
Calcium-binding protein critical for proper photoreceptor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process. {ECO:0000269PubMed:23023331}.
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Subcellular Localization |
Photoreceptor inner segment. Cell membrane, sarcolemma. Note=Expressed in inner and outer segments of photoreceptor cells, as well as in the pigmented epithelium. Also observed in the inner and outer plexiform layers and in the ganglion cell layer. Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ).
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Disease Associations |
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Tissue Specificity |
Expressed in the muscle, retina, megakaryocytes and endothelial cells. {ECO:0000269PubMed:18611855, ECO:0000269PubMed:18989529, ECO:0000269PubMed:23023331}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1929293
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InterPro |
IPR002048
EF-hand domain
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PFAM |
PF00036
PF13202
PF13405
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PRINTS |
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PIRSF |
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SMART |
SM00054
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Z309
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q544Z8
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UniProt Splice Variant |
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Entrez Gene |
56506
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UniGene |
Mm.42192
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RefSeq |
NP_062660
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MGI ID |
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MGI Symbol |
Cib2
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OMIM |
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CCDS |
CCDS40642
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HPRD |
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IMGT |
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EMBL |
AB016080
AK005347
AK013240
BC005739
CH466522
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GenPept |
AAH05739
BAA36545
BAB23968
BAB28737
EDL25816
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