Mus musculus Protein: Gzmd
Summary
InnateDB Protein IDBP-166783.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gzmd
Protein Name granzyme D
Synonyms CCP5; Ctla-5; Ctla5;
Species Mus musculus
Ensembl Protein ENSMUSP00000080742
InnateDB Gene IDBG-166781 (Gzmd)
Protein Structure
UniProt Annotation
Function This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.
Subcellular Localization Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019835 cytolysis
Cellular Component
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID MGI:109255
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P11033
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 14941
UniGene Mm.482071
RefSeq NP_034502
MGI ID
MGI Symbol Gzmd
OMIM
CCDS CCDS49502
HPRD
IMGT
EMBL AC091783 AK131671 BC141122 J03255 U66472
GenPept AAA37736 AAB19190 AAI41123 BAE20756