InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cyp2d22

Summary

InnateDB Protein

IDBP-166882.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Cyp2d22

Protein Name

cytochrome P450, family 2, subfamily d, polypeptide 22

Synonyms

2D22;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023083

InnateDB Gene

IDBG-166880 (Cyp2d22)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0004509	steroid 21-monooxygenase activity
GO:0005506	iron ion binding
GO:0008391	arachidonic acid monooxygenase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0020037	heme binding

Biological Process

GO:0007565	female pregnancy
GO:0010033	response to organic substance
GO:0017144	drug metabolic process
GO:0019369	arachidonic acid metabolic process
GO:0042416	dopamine biosynthetic process
GO:0042417	dopamine metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:1929474

InterPro

IPR001128 Cytochrome P450
IPR002397 Cytochrome P450, B-class
IPR002401 Cytochrome P450, E-class, group I
IPR002403 Cytochrome P450, E-class, group IV
IPR008069 Cytochrome P450, E-class, group I, CYP2D-like

PFAM

PF00067

PRINTS

PR00385
PR00359
PR00463
PR00465
PR01686

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite