Mus musculus Protein: Gzmf
Summary
InnateDB Protein IDBP-166916.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gzmf
Protein Name granzyme F
Synonyms CCP4; Ctla-7; Ctla7; MCSP-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000022757
InnateDB Gene IDBG-166914 (Gzmf)
Protein Structure
UniProt Annotation
Function This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.
Subcellular Localization Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019835 cytolysis
Cellular Component
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID MGI:109254
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08883
PhosphoSite PhosphoSite-P08883
TrEMBL Q497Z7
UniProt Splice Variant
Entrez Gene 14943
UniGene Mm.470274
RefSeq NP_034504
MGI ID
MGI Symbol Gzmf
OMIM
CCDS CCDS36936
HPRD
IMGT
EMBL BC100311 BC145435 CH466535 J03257 M36902 M96930 X12823 X14094 X56989
GenPept AAA37488 AAA37738 AAA37741 AAI00312 AAI45436 CAA31310 CAA32256 CAA40307 EDL36205