Version 5.4
Mus musculus Protein: Catsperg2
Summary
InnateDB Protein IDBP-167066.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Catsperg2
Protein Name cation channel, sperm-associated, gamma 2
Synonyms 1700067C01Rik; CATSPERG;
Species Mus musculus
Ensembl Protein ENSMUSP00000052285
InnateDB Gene IDBG-167064 (Catsperg2)
Protein Structure
UniProt Annotation
Function Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. {ECO:0000269PubMed:19516020}.
Subcellular Localization Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Disease Associations
Tissue Specificity Testis-specific. Specifically expressed in the principal piece of the sperm tail (at protein level). Expressed in spermatocytes and spermatids within the seminiferous tubule but not in interstitial cells. {ECO:0000269PubMed:19516020}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0008150 biological_process
GO:0030154 cell differentiation
Cellular Component
GO:0031514 motile cilium
GO:0036128 CatSper complex
GO:0097228 sperm principal piece
Protein Structure and Domains
PDB ID MGI:1923968
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt C6KI89
PhosphoSite PhosphoSite-C6KI89
TrEMBL
UniProt Splice Variant
Entrez Gene 76718
UniGene Mm.69030
RefSeq NP_083990
MGI ID
MGI Symbol Catsperg2
OMIM
CCDS CCDS52173
HPRD
IMGT
EMBL AC112789 GQ225581
GenPept ACT09363

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca