InnateDB Protein
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IDBP-167242.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Serpina10
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Protein Name
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serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000048357
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InnateDB Gene
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IDBG-167240 (Serpina10)
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Protein Structure
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Function |
Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors (By similarity). {ECO:0000250}.
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Subcellular Localization |
Secreted {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Detectable in liver, but not in heart, brain, spleen, lung, kidney, skeletal muscle or testes. {ECO:0000269PubMed:11372680}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004867
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serine-type endopeptidase inhibitor activity
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GO:0008201
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heparin binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2667725
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InterPro |
IPR023796
Serpin domain
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PFAM |
PF00079
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PRINTS |
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PIRSF |
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SMART |
SM00093
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TIGRFAMs |
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Modification |
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SwissProt |
Q8R121
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
217847
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UniGene |
Mm.29094
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RefSeq |
NP_659083
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MGI ID |
4AJT
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MGI Symbol |
Serpina10
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OMIM |
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CCDS |
CCDS26134
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HPRD |
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IMGT |
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EMBL |
AY324633
BC018416
BC025821
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GenPept |
AAH18416
AAH25821
AAP87100
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