Version 5.4
Mus musculus Protein: Marveld1
Summary
InnateDB Protein IDBP-167248.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Marveld1
Protein Name MARVEL (membrane-associating) domain containing 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000053733
InnateDB Gene IDBG-167246 (Marveld1)
Protein Structure
UniProt Annotation
Function Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration. {ECO:0000269PubMed:21347699}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:21347699}; Multi-pass membrane protein {ECO:0000269PubMed:21347699}. Nucleus {ECO:0000269PubMed:21347699}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:21347699}. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007049 cell cycle
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2147570
InterPro IPR008253 Marvel domain
PFAM PF01284
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TQJ1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 277010
UniGene Mm.206250
RefSeq NP_899018
MGI ID
MGI Symbol Marveld1
OMIM
CCDS CCDS50439
HPRD
IMGT
EMBL AK081212 AK132243 BC054384
GenPept AAH54384 BAC38165 BAE21054

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca