Version 5.4
Mus musculus Protein: Serpina6
Summary
InnateDB Protein IDBP-167281.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpina6
Protein Name serine (or cysteine) peptidase inhibitor, clade A, member 6
Synonyms AI265318; AV104445; Cbg;
Species Mus musculus
Ensembl Protein ENSMUSP00000044033
InnateDB Gene IDBG-167279 (Serpina6)
Protein Structure
UniProt Annotation
Function Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed by the liver; secreted in plasma.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005496 steroid binding
Biological Process
GO:0006810 transport
GO:0008211 glucocorticoid metabolic process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:88278
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q06770
PhosphoSite PhosphoSite-
TrEMBL D3Z2I9
UniProt Splice Variant
Entrez Gene 12401
UniGene Mm.413558
RefSeq NP_031644
MGI ID
MGI Symbol Serpina6
OMIM
CCDS CCDS26135
HPRD
IMGT
EMBL AC125360 X70533
GenPept CAA49934

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca