Version 5.4
Mus musculus Protein: Serpina1d
Summary
InnateDB Protein IDBP-167489.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpina1d
Protein Name serine (or cysteine) peptidase inhibitor, clade A, member 1D
Synonyms AI118301; Dom4; PI4; Spi1-4;
Species Mus musculus
Ensembl Protein ENSMUSP00000077909
InnateDB Gene IDBG-167487 (Serpina1d)
Protein Structure
UniProt Annotation
Function Inhibitor of serine proteases. Can inhibit trypsin and chymotrypsin; relatively ineffective against elastase. {ECO:0000269PubMed:11961105, ECO:0000269PubMed:8619829}.
Subcellular Localization Secreted {ECO:0000269PubMed:11961105, ECO:0000269PubMed:8619829}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0034097 response to cytokine
GO:0043434 response to peptide hormone
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:891968
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q00897
PhosphoSite PhosphoSite-Q00897
TrEMBL
UniProt Splice Variant
Entrez Gene 20703
UniGene
RefSeq NP_033272
MGI ID
MGI Symbol Serpina1d
OMIM
CCDS CCDS26139
HPRD
IMGT
EMBL AK002537 M75718
GenPept AAC28867 BAB22173

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca