Version 5.4
Mus musculus Protein: Cast
Summary
InnateDB Protein IDBP-167764.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Cast
Protein Name calpastatin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000065275
InnateDB Gene IDBG-167762 (Cast)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0010466 negative regulation of peptidase activity
GO:0030163 protein catabolic process
GO:2000675 negative regulation of type B pancreatic cell apoptotic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1098236
InterPro IPR001259 Proteinase inhibitor I27, calpastatin
PFAM PF00748
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q921U7
UniProt Splice Variant
Entrez Gene 12380
UniGene Mm.29163
RefSeq NP_033947
MGI ID
MGI Symbol Cast
OMIM
CCDS CCDS26648
HPRD
IMGT
EMBL AC138120 AC154780 AK028843 AK089108 BC010603
GenPept AAH10603 BAC26149 BAC40755

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca