Version 5.4
Mus musculus Protein: S100a3
Summary
InnateDB Protein IDBP-167930.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100a3
Protein Name S100 calcium binding protein A3
Synonyms S100E;
Species Mus musculus
Ensembl Protein ENSMUSP00000001047
InnateDB Gene IDBG-167926 (S100a3)
Protein Structure
UniProt Annotation
Function Binds both calcium and zinc. May be involved in calcium- dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Skin specific, specifically expressed in cuticle of pelage follicle. {ECO:0000269PubMed:9804353}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1338849
InterPro IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
PFAM PF01023
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P62818
PhosphoSite PhosphoSite-
TrEMBL Q496W1
UniProt Splice Variant
Entrez Gene 20197
UniGene
RefSeq NP_035440
MGI ID
MGI Symbol S100a3
OMIM
CCDS CCDS17537
HPRD
IMGT
EMBL AF004941 AF087470 AK133717 BC099893 BC100690 BC100696 BC100697 CH466547
GenPept AAC64107 AAC78730 AAH99893 AAI00691 AAI00697 AAI00698 BAE21797 EDL15117 EDL15118

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca