InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd320

Summary

InnateDB Protein

IDBP-168062.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd320

Protein Name

CD320 antigen

Synonyms

425O18-1; 8D6; CD320-002; D17Ertd716e; NG29; VLDL;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000002379

InnateDB Gene

IDBG-168060 (Cd320)

Protein Structure

UniProt Annotation

Function

Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0031419	cobalamin binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome