InnateDB Protein
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IDBP-168202.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ttll1
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Protein Name
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tubulin tyrosine ligase-like 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000016897
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InnateDB Gene
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IDBG-168200 (Ttll1)
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Protein Structure
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Function |
Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. {ECO:0000269PubMed:15890843}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Widely expressed with highest levels in brain, heart and kidney. {ECO:0000269PubMed:17499049}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2443047
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InterPro |
IPR004344
Tubulin-tyrosine ligase/Tubulin polyglutamylase
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PFAM |
PF03133
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91V51
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q8BJG7
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UniProt Splice Variant |
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Entrez Gene |
319953
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UniGene |
Mm.427774
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RefSeq |
NP_849200
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MGI ID |
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MGI Symbol |
Ttll1
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OMIM |
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CCDS |
CCDS27702
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HPRD |
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IMGT |
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EMBL |
AK031917
AK047046
AK084005
AK140472
AK168786
AK169150
AL583887
AL583889
BC010510
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GenPept |
AAH10510
BAC27603
BAC32947
BAC39092
BAE24404
BAE40620
BAE40929
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