Mus musculus Protein: Gja3
Summary
InnateDB Protein IDBP-168217.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gja3
Protein Name gap junction protein, alpha 3
Synonyms Cnx46; Cx43; Cx46; Gja-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000059587
InnateDB Gene IDBG-168215 (Gja3)
Protein Structure
UniProt Annotation
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular Localization Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005243 gap junction channel activity
Biological Process
GO:0007154 cell communication
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0005922 connexon complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:95714
InterPro IPR000500 Connexin
IPR002262 Gap junction alpha-3 protein (Cx46)
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain
PFAM PF00029
PF10582
PRINTS PR00206
PR01133
PIRSF
SMART SM00037
SM01089
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q64448
PhosphoSite PhosphoSite-
TrEMBL Q6TPJ2
UniProt Splice Variant
Entrez Gene 14611
UniGene
RefSeq NP_058671
MGI ID
MGI Symbol Gja3
OMIM
CCDS CCDS27152
HPRD
IMGT
EMBL AK136383 AY390398 AY390399 BC138492 BC138493 CH466535 U44955
GenPept AAB03211 AAI38493 AAI38494 AAQ93031 AAQ93032 BAE22957 EDL36182 EDL36184