Version 5.4
Mus musculus Protein: Serpina3n
Summary
InnateDB Protein IDBP-168303.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpina3n
Protein Name serine (or cysteine) peptidase inhibitor, clade A, member 3N
Synonyms Spi2-2; Spi2.2; Spi2/eb.4;
Species Mus musculus
Ensembl Protein ENSMUSP00000021506
InnateDB Gene IDBG-168301 (Serpina3n)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0006954 inflammatory response
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0032496 response to lipopolysaccharide
GO:0034097 response to cytokine
GO:0034516 response to vitamin B6
GO:0043434 response to peptide hormone
GO:0071320 cellular response to cAMP
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071354 cellular response to interleukin-6
GO:0071385 cellular response to glucocorticoid stimulus
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:105045
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3X8T9
UniProt Splice Variant
Entrez Gene 20716
UniGene Mm.482074
RefSeq NP_033278
MGI ID
MGI Symbol Serpina3n
OMIM
CCDS CCDS26152
HPRD
IMGT
EMBL AC117194 CH466549
GenPept EDL18789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca