InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cryl1

Summary

InnateDB Protein

IDBP-168327.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cryl1

Protein Name

crystallin, lambda 1

Synonyms

1110025H08Rik; A230106J09Rik; C85932; gul3dh;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022517

InnateDB Gene

IDBG-168325 (Cryl1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed, with highest levels in liver. Undetectable in skeletal muscle. {ECO:0000269PubMed:12527201}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0042803	protein homodimerization activity
GO:0050104	L-gulonate 3-dehydrogenase activity
GO:0070403	NAD+ binding

Biological Process

GO:0006631	fatty acid metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1915881

InterPro

IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like

PFAM

PF00725
PF02737

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99KP3

PhosphoSite