Version 5.4
Mus musculus Protein: Cox15
Summary
InnateDB Protein IDBP-168368.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cox15
Protein Name COX15 homolog, cytochrome c oxidase assembly protein (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000041820
InnateDB Gene IDBG-168366 (Cox15)
Protein Structure
UniProt Annotation
Function May be involved in the biosynthesis of heme A. {ECO:0000250}.
Subcellular Localization Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
Biological Process
GO:0006784 heme a biosynthetic process
GO:0008535 respiratory chain complex IV assembly
GO:0055114 oxidation-reduction process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1920112
InterPro IPR003780 Heme A synthase
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF02628
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BJ03
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 226139
UniGene Mm.472925
RefSeq NP_659123
MGI ID
MGI Symbol Cox15
OMIM
CCDS CCDS29836
HPRD
IMGT
EMBL AK048099 AK141631 BC011509 BC021498
GenPept AAH11509 AAH21498 BAC33241 BAE24776

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca